Hypertension patients will be cured with this medicine, clinical trial started

About 32% of the world’s adult population today suffers from hypertension. In India, 1 out of every 3 people is a patient with high blood pressure. This is the reason why the demand for medicines that reduce blood pressure is increasing. Different types of side effects are being seen in existing medicines that reduce blood pressure. Because of this, the pressure of finding new anti-hypertensive drugs is constantly increasing.

Hypertension patients will be cured with this medicine, clinical trial started

This medicine will reduce blood pressure
Scientists in the pharmacy department of Banasthali Vidyapith have discovered a new anti-hypertensive drug, which will reduce blood pressure in the future. This will also help in the treatment of Angina and other heart-related diseases. This research work has been published in the prestigious American Chemical Society Journal in August 2020.


Medicine made using computer software
The Head of the Department of Pharmacy of Banasthali University Prof. Research conducted by Sarvesh Paliwal and his team members, Dr. Swapnil Sharma and Dr. Seema Kesar, has found that this drug inhibits the enzyme (Enzyme) named ROCK (RHO kinase). The ROCK (RHO kinase) enzyme is an important cause of increased blood pressure in humans. This drug shows its effect on rock enzyme 2. It is notable and important here that only one drug of this class is Fasudil, which is available in Japan (Japan) and China (China). He also has the patent rights of this drug. Therefore, this research has a special significance in the context of India and other parts of the world. Pro. According to Paliwal, the Computer-Aided Drug Design-CADD technique has played a very important role in the discovery of this drug. CADD is a computer technique in which new drugs can be discovered using different computer software.

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5 years of research
Pro. Paliwal said that this research work was started 5 years ago and after testing about 3 lakh samples, he got success. After testing on mice, it was discovered that this drug could be seen as an alternative to high blood pressure medications in the future. Pro. According to Paliwal, in the entire funding of this project, Vice-Chancellor, Vice-Chancellor of Banasthali Vidyapith, Prof. Aditya Shastri has made an unprecedented contribution. He continuously encouraged the team members in this research work.

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After the success of this research work, the scientists of Banasthali Vidyapith have started the process of the next phase i.e. Clinical Trial.



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